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Vestigial-like family member 3

protein-coding gene in the species Homo sapiens

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Science and natureInterpretive dossier study · Crown Archives visual atlas
Record originEnglish Wikipedia
Text licenseCC BY-SA 4.0
Source revisionSep 19, 2026
Entity authorityQ18056613 ↗
Source-derived summary

Vestigial-like family member 3 is a protein that in humans is encoded by the VGLL3 gene.

This protein is one of four mammalian homologs (VGLL1-4) of the vestigial gene found in the fruit fly Drosophila. VGLL3 functions as a transcription coregulator by binding to TEA domain (TEAD) transcription factors (TEAD1, TEAD2, TEAD3, TEAD4 ) through its TDU motif. VGLL3 has been implicated in various biological processes including myogenesis (formation of muscle tissue), cell proliferation, and cancer progression. VGLL3 can also promote epithelial-to-mesenchymal transition (EMT) and cell motility in certain cancer types, suggesting it may play a role in tumor development and metastasis.

Editorial summary

“Vestigial-like family member 3” enters the record as protein-coding gene in the species Homo sapiens. Crown Archives preserves that source wording while asking what Vestigial-like, family and member can confirm, complicate or overturn.

Editorial reviewA sound reference starting point where classification, measurement and the date of the underlying evidence remain visible. The current 102-word lead offers orientation but no explicit four-digit date, so chronology should not be assumed. The selected authority fields contribute no independent date. Its strongest next move is a source search built around Vestigial-like, family and member.
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“Vestigial-like family member 3” is worth following because a concise public description often conceals a longer documentary argument. Here, Vestigial-like, family and member provides the most credible route into that argument.

Evidence profile

Stable identifiers, scientific names and standards terminology offer the best bridge between this overview and specialist evidence. The source revision retrieved here is dated Sep 19, 2026. The linked authority identifier is Q18056613. None of the 0 selected statements returned an explicit reference.

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This entry incorporates text from “Vestigial-like family member 3” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.