UGT2A2
protein-coding gene in the species Homo sapiens
UDP glucuronosyltransferase 2 family, polypeptide A2, also known as UGT2A2, is an enzyme that in humans is encoded by the UGT2A2 gene.
Function
The olfactory neuroepithelium, which lines the posterior nasal cavity, is exposed to a wide range of odorants and airborne toxic compounds. Odorants, which are mostly small lipophilic molecules, enter the mucus flow and reach the odorant receptors on sensory neurons. Odorant sensing is generally a transient process, requiring an effective signal termination, which could be provided by biotransformation of the odorant in the epithelial supporting cells. Xenobiotic-metabolizing enzymes in the olfactory epithelium have been suggested to catalyze inactivation and facilitate elimination of odorants. UGT2A1 and UGT2A2 were recently implicated as having a role in the loss of smell symptom associated with COVID-19.
References
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
The public source identifies “UGT2A2” as protein-coding gene in the species Homo sapiens. This brief keeps that definition visible, then builds a research path around UGT2A2, protein-coding and gene.
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The date and method of observation matter as much as the stated conclusion, especially where classification or consensus has changed. The source revision retrieved here is dated Jan 27, 2026. The linked authority identifier is Q18059258. None of the 0 selected statements returned an explicit reference.
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This entry incorporates text from “UGT2A2” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.