CACrown ArchivesThe cinema collection
EN/FR
Search
Menu
Research dossier · General Reference

Galactosylxylosylprotein 3-beta-galactosyltransferase

class of enzymes

Cross-disciplinary reference desk with index cards, atlas, dictionary and catalogue
General referenceInterpretive dossier study · Crown Archives visual atlas
Record originEnglish Wikipedia
Text licenseCC BY-SA 4.0
Source revisionJul 5, 2025
Entity authorityQ5517848 ↗
Source-derived summary

In enzymology, a galactosylxylosylprotein 3-beta-galactosyltransferase (EC 2.4.1.134) is an enzyme that catalyzes the chemical reaction

UDP-galactose + 4-beta-D-galactosyl-O-beta-D-xylosylprotein

⇌

{\displaystyle \rightleftharpoons }

UDP + 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein

Thus, the two substrates of this enzyme are UDP-galactose and 4-beta-D-galactosyl-O-beta-D-xylosylprotein, whereas its two products are UDP and 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-galactose:4-beta-D-galactosyl-O-beta-D-xylosylprotein 3-beta-D-galactosyltransferase. Other names in common use include galactosyltransferase II, and uridine diphosphogalactose-galactosylxylose galactosyltransferase. This enzyme participates in chondroitin sulfate biosynthesis and glycan structures - biosynthesis 1. It employs one cofactor, manganese.

References

Robinson JA, Robinson HC (1985). "Initiation of chondroitin sulphate synthesis by beta-D-galactosides Substrates for galactosyltransferase II". Biochem. J. 227 (3): 805–14.

Editorial summary

The public source identifies “Galactosylxylosylprotein 3-beta-galactosyltransferase” as class of enzymes. This brief keeps that definition visible, then builds a research path around Galactosylxylosylprotein, 3-beta-galactosyltransferase and class.

Editorial reviewA practical starting point whose main value is the path it opens into stronger specialist and primary sources. The current lead gives the account dated anchors—1985—that can be checked directly. The selected authority fields contribute no independent date. Its value is orientation rather than verdict, with Galactosylxylosylprotein, 3-beta-galactosyltransferase and class providing the first useful test.
Editorial analysis

Why this record matters

A short description can identify a subject without explaining its stakes. For “Galactosylxylosylprotein 3-beta-galactosyltransferase”, the useful work is to connect “class of enzymes” to the records capable of establishing context and consequence.

Evidence profile

Vocabulary and entity names are the principal evidence signals here, because they determine the precision of every later search. The source revision retrieved here is dated Jul 5, 2025. The linked authority identifier is Q5517848. None of the 0 selected statements returned an explicit reference. The first chronological checks are 1985.

Critical limits

A concise general-reference account can conceal disagreements about scope, terminology or the weight assigned to individual sources. The lead is largely declarative, so disagreement and counter-evidence require a deliberate search beyond the opening account. Authority statements aid reconciliation but still require their own references, qualifiers and ranks to be checked.

How to read it

Use the entry as an orientation point, then follow its citations and revision history. Names, dates and institutional relationships should be checked against the original record.

Best used for
  • Subject orientation
  • Search vocabulary
  • Locating named sources
Verify next

The closest primary source, responsible institution and strongest cited specialist reference.

Three-step research path

  1. Establish the record: confirm the title “Galactosylxylosylprotein 3-beta-galactosyltransferase”, its source revision and the description used here.
  2. Expand the search: follow Galactosylxylosylprotein 3-beta-galactosyltransferase primary sources, Galactosylxylosylprotein 3-beta-galactosyltransferase archive and Galactosylxylosylprotein research across catalogues and specialist indexes.
  3. Test the account: compare the strongest cited source with the responsible institution’s current record and note any disagreement.

Questions for further research

  1. Which source most directly establishes the central claim about “Galactosylxylosylprotein 3-beta-galactosyltransferase”?
  2. What terminology or title could unlock a more precise catalogue search?
  3. Which institution is responsible for the underlying evidence?
Subject index

Search terms from this dossier

Source & attribution

This entry incorporates text from “Galactosylxylosylprotein 3-beta-galactosyltransferase” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.