Treacher Collins syndrome
human genetic disorder
Treacher Collins syndrome (TCS) is a genetic disorder characterized by deformities of the ears, eyes, cheekbones, and chin. The degree to which a person is affected may vary from mild to severe. Complications may include breathing problems, vision problems, cleft palate, and hearing loss. Those affected generally have normal intelligence.
TCS is usually autosomal dominant. More than half of occurrences are as a result of a new mutation rather than inherited. The involved genes may include TCOF1, POLR1C, or POLR1D. Diagnosis is generally based on symptoms and X-rays, and potentially confirmation by genetic testing.
Treacher Collins syndrome is not curable. Symptoms may be managed with reconstructive surgery, hearing aids, speech therapy, and other assistive devices. Life expectancy is generally normal.
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The citation trail is more important than the brevity of the summary: it shows where individual claims can be examined in context. The source revision retrieved here is dated Sep 10, 2026. The linked authority identifier is Q744790. None of the 0 selected statements returned an explicit reference.
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This entry incorporates text from “Treacher Collins syndrome” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.