Toungoo–Hanthawaddy War
16th-century military conflict in Asia

The Toungoo–Hanthawaddy War (1534–1541) (Burmese: တောင်ငူ–ဟံသာဝတီ စစ် (၁၅၃၄–၁၅၄၁)) was a military conflict between the Toungoo Kingdom, and the Hanthawaddy kingdom and its allies the Prome Kingdom and the Confederation of Shan States that took place in present-day Lower Burma (Myanmar) between 1534 and 1541. In a series of improbable events, the upstart Burmese-speaking kingdom defeated the Mon-speaking Hanthawaddy, the most prosperous and powerful of all post-Pagan kingdoms before the war. In the following years, Toungoo used the newly acquired kingdom's wealth and manpower to reunify the various petty states that had existed since the fall of Pagan Empire in 1287.
Background
Since its founding in 1279 as an outpost of the Pagan Kingdom, Toungoo, located in a remote, hard-to-reach corner east of the Pegu Yoma (Bago Yoma) range, had always been a troublesome province for its overlord. During the Ava period, its governors and viceroys raised multiple rebellions (1427–1428, 1437–1442, 1451–1458, and 1468–1470), each time with clandestine or open help from Hanthawaddy, which wanted to keep Ava unstable.
Ironically, Toungoo would repay by attacking Hanthawaddy itself. Circa 1494, Toungoo, then still a vassal of Ava, raided Hanthawaddy's territory, taking advantage of the larger kingdom's succession crisis. But Hanthawaddy's new king Binnya Ran II retaliated by laying siege to Toungoo in 1495–1496. Toungoo barely survived the siege; Mingyi Nyo, viceroy of Toungoo, would not provoke the larger neighbor for the remainder of his life. After he declared independence from Ava in 1510, Mingyi Nyo largely stayed out of the fighting raging between Ava and the Confederation of Shan States.
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