Bis(2,2,6,6-tetramethyl-4-piperidyl) sebacate
antioxidant stabilizer for protecting plastics and polymers from light-induced free radicals

Bis(2,2,6,6-tetramethyl-4-piperidyl) sebacate (abbreviated BTMPS) is a hindered amine light stabilizer used to protect plastics and coatings such as paint from oxidation caused by sunlight weathering. Like most compounds of this class, the activated form is an aminoxyl radical.
Synthesis
It is produced by the diesterification of sebacic acid (decanedioic acid) with 4-hydroxy-TEMPO.
Public health and medical concerns
In 2024, it was detected as an adulterant in illicitly sold fentanyl in the United States.
It is capable of inhibiting nicotinic acetylcholine receptors. Additionally, it is a potent blocker of L-type calcium channels. It is also able to induce dose-dependent hemodynamic alterations. Similar to early calcium channel blockers, it can precipitate adrenergic release.
See also
Antioxidant
Photolysis (photodegradation)
Radical (chemistry)
References
External links
"Weird chemical used in plastics has erupted as latest fentanyl adulterant". Ars Technica. 2025-07-10.
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This entry incorporates text from “Bis(2,2,6,6-tetramethyl-4-piperidyl) sebacate” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.