Timeline of early HIV/AIDS cases
Open-knowledge reference entry

HIV/AIDS was recognised as a novel illness in the early 1980s. An AIDS case is classified as "early" if the death occurred before 5 June 1981, when the AIDS epidemic was formally recognized by medical professionals in the United States.
Virus origins
All known subgroups of HIV-1 and HIV-2 are thought to have entered humans as distinct cross-species transmissions of simian immunodeficiency virus (SIV) from primates.
SIV exists as distinct lineages that cluster in different species of primates. HIV-1 is most similar to the SIV found in common chimpanzees (SIVcpz) in southeastern Cameroon, giving rise to the notion that HIV-1 emerged from chimpanzees in this area. SIVcpz itself emerged in chimpanzees as the result of a recombination of two separate lineages of SIV known to infect red-capped mangabey, and Cercopithecus species.
Early 20th century
HIV-1 group M (responsible for the global pandemic) is estimated to have emerged in humans around 1920 near Kinshasa, then part of the Belgian Congo. This estimation was the result of time-scaled evolutionary models being applied to modern samples and retrieved early samples of HIV-1 (M). It had previously been estimated from the genetic differences between LEO70 and DRC60 samples and later samples that HIV-1 group M had jumped into humans in 1908 ± 10 years.
1950s
The earliest known sample of HIV-1 is from Kinshasa, Democratic Republic of the Congo (DRC) (formerly Zaire, formerly the Belgian Congo).
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