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Dopaminergic cell groups

type of group of cells

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Record originEnglish Wikipedia
Text licenseCC BY-SA 4.0
Source revisionJan 4, 2026
Entity authorityQ5297290 ↗
Source-derived summary

Dopaminergic cell groups, DA cell groups, or dopaminergic nuclei are collections of neurons in the central nervous system that synthesize the neurotransmitter dopamine. In the 1960s, dopaminergic neurons or dopamine neurons were first identified and named by Annica Dahlström and Kjell Fuxe, who used histochemical fluorescence. The subsequent discovery of genes encoding enzymes that synthesize dopamine, and transporters that incorporate dopamine into synaptic vesicles or reclaim it after synaptic release, enabled scientists to identify dopaminergic neurons by labeling gene or protein expression that is specific to these neurons.

In the mammalian brain, dopaminergic neurons form a semi-continuous population extending from the midbrain through the forebrain, with eleven named collections or clusters among them.

Cell group A8

Group A8 is a small group of dopaminergic cells in rodents and primates. It is located in the midbrain reticular formation dorsolateral to the substantia nigra at the level of the red nucleus and caudally. In the mouse it is identified with the retrorubral field as defined by classical stains.

Cell group A9

Group A9 is the most densely packed group of dopaminergic cells, and is located in the ventrolateral midbrain of rodents and primates. It is for the most part identical with the pars compacta of the substantia nigra as seen from the accumulation of neuromelanin pigment in the midbrain of healthy, adult humans.

Cell group A10

Group A10 is the largest group of dopaminergic cells in the ventral midbrain tegmentum of rodents and primates.

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The public source identifies “Dopaminergic cell groups” as type of group of cells. This brief keeps that definition visible, then builds a research path around Dopaminergic, cell and groups.

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This entry incorporates text from “Dopaminergic cell groups” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.