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TRNA (guanine9-N1)-methyltransferase

class of enzymes

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General referenceInterpretive dossier study · Crown Archives visual atlas
Record originEnglish Wikipedia
Text licenseCC BY-SA 4.0
Source revisionSep 10, 2026
Entity authorityQ5112732 ↗
Source-derived summary

tRNA (guanine9-N1)-methyltransferase (EC 2.1.1.221) is an enzyme with systematic name S-adenosyl-L-methionine:tRNA (guanine9-N1)-methyltransferase. This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + guanine9 in tRNA

⇌

{\displaystyle \rightleftharpoons }

S-adenosyl-L-homocysteine + N1-methylguanine9 in tRNA

The enzyme from Saccharomyces cerevisiae specifically methylates guanine9. In humans, isozymes have been found encoded by the genes TRMT10A, TRMT10B, and TRMT10C.

Alternative names

Various names have been associated with enzyme, including Trm10p, tRNA(m1G9/m1A9)-methyltransferase, tRNA(m1G9/m1A9)MTase, tRNA (guanine-N(1)-)-methyltransferase, tRNA m1G9-methyltransferase, and tRNA m1G9 MTase.

Editorial summary

“TRNA (guanine9-N1)-methyltransferase” enters the record as class of enzymes. Crown Archives preserves that source wording while asking what TRNA, guanine9-N1 and -methyltransferase can confirm, complicate or overturn.

Editorial reviewA dependable orientation record for establishing vocabulary, names and a first evidence trail. The current 76-word lead offers orientation but no explicit four-digit date, so chronology should not be assumed. The selected authority fields contribute no independent date. Its strongest next move is a source search built around TRNA, guanine9-N1 and -methyltransferase.
Editorial analysis

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“TRNA (guanine9-N1)-methyltransferase” is worth following because a concise public description often conceals a longer documentary argument. Here, TRNA, guanine9-N1 and -methyltransferase provides the most credible route into that argument.

Evidence profile

Named sources, stable identifiers and responsible institutions provide the strongest route from overview to verifiable evidence. The source revision retrieved here is dated Sep 10, 2026. The linked authority identifier is Q5112732. None of the 0 selected statements returned an explicit reference.

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Source & attribution

This entry incorporates text from “TRNA (guanine9-N1)-methyltransferase” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.