Stem cell proteomics
stem cells
Stem cell proteomics is a developing field of omics that analyzes the proteomes of stem cells. The main interest of the application of proteomics on stem cells is the identification and quantification of varying proteomes that determine stem cell differentiation. The two central components to the understanding of stem cell differentiation are cell fate and cell state. Cell fate is the likelihood a cell will differentiate into a particular type of cell. Cell state is the profiling of a type of cell using a combination of unique markers that differentiate one lineage from another. Some notable markers of cell states analyzed with proteomics include surface proteins, translation rate, and post transcriptional modifications.
Stem Cells
Stem cells are undifferentiated cells that are capable of self-replicating. The main types of stem cells are embryonic, adult, and induced pluripotent. Embryonic and induced pluripotent are most frequently studied using proteomics, since both types have more expansive capabilities in which it can be differentiated than adult stem cells. This is defined by the ability to create cells of all three germ layers: ectoderm, endoderm, and mesoderm.
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This entry incorporates text from “Stem cell proteomics” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.