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Isosorbide dinitrate

chemical compound

Specimen drawers, botanical folios and brass scientific instruments under study light
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Record originEnglish Wikipedia
Text licenseCC BY-SA 4.0
Source revisionFeb 13, 2026
Entity authorityQ179748
Source-derived summary

Isosorbide dinitrate is a medication used for heart failure, esophageal spasms, and to treat and prevent angina pectoris. It has been found to be particularly useful in heart failure due to systolic dysfunction together with hydralazine. It is taken by mouth or under the tongue.

Common side effects include headache, lightheadedness with standing, and blurred vision. Severe side effects include low blood pressure. It is unclear if use in pregnancy is safe for the baby. It should not be used together with PDE5 Inhibitors. Isosorbide dinitrate is in the nitrate family of medications and works by dilating blood vessels.

Isosorbide dinitrate was first written about in 1939. It is on the World Health Organization's List of Essential Medicines.

Editorial summary

“Isosorbide dinitrate” enters the record as chemical compound. Crown Archives preserves that source wording while asking what Isosorbide, dinitrate and chemical can confirm, complicate or overturn.

Editorial reviewUseful for establishing the present vocabulary of the subject while preserving a route back to the evidence on which that vocabulary rests. The current lead gives the account dated anchors—1939—that can be checked directly. The selected authority fields contribute no independent date. Its strongest next move is a source search built around Isosorbide, dinitrate and chemical.
Editorial analysis

Why this record matters

“Isosorbide dinitrate” is worth following because a concise public description often conceals a longer documentary argument. Here, Isosorbide, dinitrate and chemical provides the most credible route into that argument.

Evidence profile

Datasets, specimens, observations and peer-reviewed methods provide the appropriate test for the technical claims summarized here. The source revision retrieved here is dated Feb 13, 2026. The linked authority identifier is Q179748. The first chronological checks are 1939.

Critical limits

Scientific names, classifications and consensus can change while older terminology persists in catalogues and historical literature. The lead is largely declarative, so disagreement and counter-evidence require a deliberate search beyond the opening account. Authority statements aid reconciliation but still require their own references, qualifiers and ranks to be checked.

How to read it

Check terminology, classification and the date of the cited evidence. Scientific names and technical consensus can change while older records retain historical value.

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Three-step research path

  1. Establish the record: confirm the title “Isosorbide dinitrate”, its source revision and the description used here.
  2. Expand the search: follow Isosorbide dinitrate primary sources, Isosorbide dinitrate archive and Isosorbide research across catalogues and specialist indexes.
  3. Test the account: compare the strongest cited source with the responsible institution’s current record and note any disagreement.

Questions for further research

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Source & attribution

This entry incorporates text from Isosorbide dinitrate” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.