Small-blue-round-cell tumor
cancerous tumors composed of small cells which stain blue
In histopathology, a small-blue-round-cell tumour (abbreviated SBRCT), also known as a small-round-blue-cell tumor (SRBCT) or a small-round-cell tumor (SRCT), is any one of a group of malignant neoplasms that have a characteristic appearance under the microscope, i.e. consisting of small round cells that stain blue on routine H&E stained sections.
These tumors are seen more often in children than in adults. They typically represent undifferentiated cells. The predominance of blue staining is because the cells consist predominantly of nucleus, thus they have scant cytoplasm.
Examples
Tumors that belong to this group are:
Desmoplastic small-round-cell tumour
Ewing sarcoma/PNET
Neuroblastoma
Medulloblastoma
Rhabdomyosarcoma
Synovial sarcoma
Carcinoid tumor
Mesothelioma
Small cell lung cancer
Wilms' tumour
Retinoblastoma
Small-cell lymphoma
Hepatoblastoma- only the anaplastic form has round blue cells, the more common fetal and embryonal types do not
Merkel cell carcinoma
Mesenchymal chondrosarcoma
Conditions mimicking SBRCT
Endometrial stromal condensation may mimic a small-blue-round-cell tumour.
This brief starts where responsible research should: with the source description of “Small-blue-round-cell tumor” as cancerous tumors composed of small cells which stain blue. Everything that follows is an evidence route, not borrowed authority.
Why this record matters
The subject matters to the general reference register because the source frames it as cancerous tumors composed of small cells which stain blue. Its deeper value depends on whether names, dates, institutions and citations support that framing.
Named sources, stable identifiers and responsible institutions provide the strongest route from overview to verifiable evidence. The source revision retrieved here is dated Nov 24, 2025. The linked authority identifier is Q7542594. None of the 0 selected statements returned an explicit reference.
Overview language is designed for orientation and should not be treated as a substitute for the evidence cited beneath it. The source lead contains qualifying language; that uncertainty should survive quotation, summary and reuse. Authority statements aid reconciliation but still require their own references, qualifiers and ranks to be checked.
How to read it
Use the entry as an orientation point, then follow its citations and revision history. Names, dates and institutional relationships should be checked against the original record.
- Subject orientation
- Search vocabulary
- Locating named sources
The closest primary source, responsible institution and strongest cited specialist reference.
Three-step research path
- Establish the record: confirm the title “Small-blue-round-cell tumor”, its source revision and the description used here.
- Expand the search: follow Small-blue-round-cell tumor primary sources, Small-blue-round-cell tumor archive and Small-blue-round-cell research across catalogues and specialist indexes.
- Test the account: compare the strongest cited source with the responsible institution’s current record and note any disagreement.
Questions for further research
- Which source most directly establishes the central claim about “Small-blue-round-cell tumor”?
- Which cited source is closest to the event, object or claim?
- What terminology or title could unlock a more precise catalogue search?
Search terms from this dossier
This entry incorporates text from “Small-blue-round-cell tumor” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.