Signal peptidase I
class of enzymes

Signal peptidase I (EC 3.4.21.89, leader peptidase I, signal proteinase, Escherichia coli leader peptidase, eukaryotic signal peptidase, eukaryotic signal proteinase, leader peptidase, leader peptide hydrolase, leader proteinase, signal peptidase, pilin leader peptidase, SPC, prokaryotic signal peptidase, prokaryotic leader peptidase, HOSP, prokaryotic signal proteinase, propeptidase, PuIO prepilin peptidase, signal peptide hydrolase, signal peptide peptidase, signalase, bacterial leader peptidase 1) is an enzyme. This enzyme catalyses the following chemical reaction
Cleavage of hydrophobic, N-terminal signal or leader sequences
This enzyme is present in bacterial membranes and in chloroplast thylakoid membranes.
“Signal peptidase I” enters the record as class of enzymes. Crown Archives preserves that source wording while asking what Signal, peptidase and class can confirm, complicate or overturn.
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Named sources, stable identifiers and responsible institutions provide the strongest route from overview to verifiable evidence. The source revision retrieved here is dated Jul 11, 2025. The linked authority identifier is Q12646475. None of the 0 selected statements returned an explicit reference.
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This entry incorporates text from “Signal peptidase I” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.