O-sialoglycoprotein endopeptidase
class of enzymes
O-sialoglycoprotein endopeptidase (EC 3.4.24.57, glycoprotease, glycophorin A proteinase, glycoproteinase, sialoglycoprotease, sialoglycoproteinase, "OSGE") is an enzyme. This enzyme catalyses the following chemical reaction
Hydrolysis of O-sialoglycoproteins; cleaves -Arg31-Asp- bond in glycophorin A. Does not cleave unglycosylated proteins, desialylated glycoproteins or glycoproteins that are only N-glycosylated
This enzyme is secreted by the bacterium Pasteurella haemolytica.
The public source identifies “O-sialoglycoprotein endopeptidase” as class of enzymes. This brief keeps that definition visible, then builds a research path around O-sialoglycoprotein, endopeptidase and class.
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Vocabulary and entity names are the principal evidence signals here, because they determine the precision of every later search. The source revision retrieved here is dated Jul 12, 2025. The linked authority identifier is Q13099994. None of the 0 selected statements returned an explicit reference.
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This entry incorporates text from “O-sialoglycoprotein endopeptidase” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.