Blister
small pocket of fluid within the upper layers of the skin

A blister is a small pocket of body fluid (lymph, serum, plasma, blood, or pus) within the upper layers of the skin, usually caused by forceful rubbing (friction), burning, freezing, chemical exposure or infection. Most blisters are filled with a clear fluid, either serum or plasma. However, blisters can be filled with blood (known as "blood blisters") or with pus (for instance, if they become infected).
In dermatology, the words vesicle and bulla refer to blisters of smaller or greater size, respectively. Smaller blisters are also called blebs.
Etymology
The word "blister" entered English in the 14th century. It came from the Middle Dutch bluyster and was a modification of the Old French blostre, which meant a leprous nodule: a rise in the skin due to leprosy.
Causes
A blister may form when the skin has been damaged by friction or rubbing, heat, cold or chemical exposure. Fluid collects between the upper layers of skin (the epidermis) and the layers below (the dermis). This fluid cushions the tissue underneath, protecting it from further damage and allowing it to heal.
“Blister” enters the record as small pocket of fluid within the upper layers of the skin. Crown Archives preserves that source wording while asking what Blister, small and pocket can confirm, complicate or overturn.
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Vocabulary and entity names are the principal evidence signals here, because they determine the precision of every later search. The source revision retrieved here is dated Sep 7, 2026. The linked authority identifier is Q276469. The Library of Congress control number is sh85014896. None of the 1 selected statements returned an explicit reference.
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This entry incorporates text from “Blister” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.