Salsoline
chemical compound
Salsoline is a tetrahydroisoquinoline alkaloid found in some plants of the genus Salsola. Salsoline is the monomethylated metabolite of salsolinol which has been thought to contribute to Parkinson's disease. Also, this has been tied to the neuropathology of chronic alcoholism.
Related compounds
Some examples of compounds that are similar to salsoline include salsolinol, isosalsoline, norsalsolinol, and carboxysalsolinol.
Reactions
These types of compounds are able to undergo addition reactions in which additions can happen to the nitrogenous ring. Also, it is possible for the ring to break open. In the presence of NaBH4 or H2SO4, this structure may be able to undergo carbonyl chemistry, if present, and other reactions, such as substitution. Salsoline is a derivative of dopamine, meaning it is able to function in the brain like dopamine.
Medicine
Salsoline has been detected in areas of the brain that are highest in concentration with dopamine. It has been found in the frontal cortex, basal ganglia, and hypothalamus.
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The date and method of observation matter as much as the stated conclusion, especially where classification or consensus has changed. The source revision retrieved here is dated Apr 28, 2026. The linked authority identifier is Q27189551. None of the 0 selected statements returned an explicit reference.
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This entry incorporates text from “Salsoline” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.