Shimon Sakaguchi
Japanese immunologist and physician (1951-)
Shimon Sakaguchi (坂口 志文, Sakaguchi Shimon; born 19 January 1951) is a Japanese immunologist. He is a distinguished professor at Osaka University and a professor emeritus at Kyoto University.
His work includes the discovery of regulatory T cells and describing their role in the immune system. In 2025, he was jointly awarded the Nobel Prize in Physiology or Medicine with Mary E. Brunkow and Fred Ramsdell.
Early life and education
Shimon Sakaguchi was born on 19 January 1951 in Nagahama, Shiga. He received a medical degree in 1976 from the Faculty of Medicine at Kyoto University. In 1982, he also received a PhD degree from Kyoto University.
Career
Sakaguchi undertook postdoctoral research in the United States at Johns Hopkins University and Stanford University from 1983 to 1987 as a Lucille P. Markey Scholar. Later, he worked as an assistant professor in the Department of Immunology at the Scripps Research Institute.
After returning to Japan in 1991, he worked at Riken as an investigator of the Japan Science and Technology Agency.
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This entry incorporates text from “Shimon Sakaguchi” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.