STEAP2
protein-coding gene in the species Homo sapiens
Metalloreductase STEAP2 is an enzyme that in humans is encoded by the STEAP2 gene.
This gene is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol.
A highly similar protein in mouse has both ferri reductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
“STEAP2” enters the record as protein-coding gene in the species Homo sapiens. Crown Archives preserves that source wording while asking what STEAP2, protein-coding and gene can confirm, complicate or overturn.
Why this record matters
“STEAP2” is worth following because a concise public description often conceals a longer documentary argument. Here, STEAP2, protein-coding and gene provides the most credible route into that argument.
The date and method of observation matter as much as the stated conclusion, especially where classification or consensus has changed. The source revision retrieved here is dated Jul 17, 2025. The linked authority identifier is Q18053941. None of the 0 selected statements returned an explicit reference.
A general summary may omit uncertainty, sample limits or methodological disagreement that is explicit in the technical record. The lead is largely declarative, so disagreement and counter-evidence require a deliberate search beyond the opening account. Authority statements aid reconciliation but still require their own references, qualifiers and ranks to be checked.
How to read it
Check terminology, classification and the date of the cited evidence. Scientific names and technical consensus can change while older records retain historical value.
- Current terminology
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- Finding cited technical literature
Primary datasets, specimen catalogues, standards bodies and the most recent peer-reviewed literature.
Three-step research path
- Establish the record: confirm the title “STEAP2”, its source revision and the description used here.
- Expand the search: follow STEAP2 primary sources, STEAP2 archive and STEAP2 research across catalogues and specialist indexes.
- Test the account: compare the strongest cited source with the responsible institution’s current record and note any disagreement.
Questions for further research
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This entry incorporates text from “STEAP2” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.