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Steroidogenic acute regulatory protein, mitochondrial

protein-coding gene in the species Homo sapiens

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Record originEnglish Wikipedia
Text licenseCC BY-SA 4.0
Source revisionJul 13, 2026
Entity authorityQ18031748 ↗
Source-derived summary

Steroidogenic acute regulatory protein is a protein that in humans is encoded by the STAR gene.

Function

The protein encoded by this gene plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH. A pseudogene of this gene is located on chromosome 13. [provided by RefSeq, Jul 2008].

References

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

Editorial summary

“Steroidogenic acute regulatory protein, mitochondrial” enters the record as protein-coding gene in the species Homo sapiens. Crown Archives preserves that source wording while asking what Steroidogenic, acute and regulatory can confirm, complicate or overturn.

Editorial reviewUseful for establishing the present vocabulary of the subject while preserving a route back to the evidence on which that vocabulary rests. The current lead gives the account dated anchors—2008—that can be checked directly. The selected authority fields contribute no independent date. Its strongest next move is a source search built around Steroidogenic, acute and regulatory.
Editorial analysis

Why this record matters

“Steroidogenic acute regulatory protein, mitochondrial” is worth following because a concise public description often conceals a longer documentary argument. Here, Steroidogenic, acute and regulatory provides the most credible route into that argument.

Evidence profile

The date and method of observation matter as much as the stated conclusion, especially where classification or consensus has changed. The source revision retrieved here is dated Jul 13, 2026. The linked authority identifier is Q18031748. None of the 0 selected statements returned an explicit reference. The first chronological checks are 2008.

Critical limits

Scientific names, classifications and consensus can change while older terminology persists in catalogues and historical literature. The lead is largely declarative, so disagreement and counter-evidence require a deliberate search beyond the opening account. Authority statements aid reconciliation but still require their own references, qualifiers and ranks to be checked.

How to read it

Check terminology, classification and the date of the cited evidence. Scientific names and technical consensus can change while older records retain historical value.

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  1. Establish the record: confirm the title “Steroidogenic acute regulatory protein, mitochondrial”, its source revision and the description used here.
  2. Expand the search: follow Steroidogenic acute regulatory protein, mitochondrial primary sources, Steroidogenic acute regulatory protein, mitochondrial archive and Steroidogenic research across catalogues and specialist indexes.
  3. Test the account: compare the strongest cited source with the responsible institution’s current record and note any disagreement.

Questions for further research

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Source & attribution

This entry incorporates text from “Steroidogenic acute regulatory protein, mitochondrial” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.