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Serotonin–norepinephrine releasing agent

drug class

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General referenceInterpretive dossier study · Crown Archives visual atlas
Record originEnglish Wikipedia
Text licenseCC BY-SA 4.0
Source revisionFeb 21, 2026
Entity authorityQ18357108 ↗
Source-derived summary

A serotonin–norepinephrine releasing agent (SNRA) is a type of drug which induces the release of serotonin and norepinephrine (and epinephrine) in the body and/or brain.

Only a few SNRAs are known, examples of which include norfenfluramine, (R)-MDMA, MBDB, and MDAI. Fenfluramine produces norfenfluramine as a major active metabolite and hence is an SNRA similarly. It was formerly used as an appetite suppressant for the treatment of obesity. (R)-MDMA, MBDB, and MDAI are entactogens. Dexfenfluramine is also an SNRA.

A closely related type of drug is a serotonin–norepinephrine reuptake inhibitor (SNRI).

Editorial summary

This brief starts where responsible research should: with the source description of “Serotonin–norepinephrine releasing agent” as drug class. Everything that follows is an evidence route, not borrowed authority.

Editorial reviewA concise reference frame for defining the subject, testing terminology and identifying the institution closest to the evidence. The current 90-word lead offers orientation but no explicit four-digit date, so chronology should not be assumed. The selected authority fields contribute no independent date. The account is most persuasive where Serotonin, norepinephrine and releasing can be independently traced.
Editorial analysis

Why this record matters

The subject matters to the general reference register because the source frames it as drug class. Its deeper value depends on whether names, dates, institutions and citations support that framing.

Evidence profile

Named sources, stable identifiers and responsible institutions provide the strongest route from overview to verifiable evidence. The source revision retrieved here is dated Feb 21, 2026. The linked authority identifier is Q18357108. None of the 0 selected statements returned an explicit reference.

Critical limits

Overview language is designed for orientation and should not be treated as a substitute for the evidence cited beneath it. The source lead contains qualifying language; that uncertainty should survive quotation, summary and reuse. Authority statements aid reconciliation but still require their own references, qualifiers and ranks to be checked.

How to read it

Use the entry as an orientation point, then follow its citations and revision history. Names, dates and institutional relationships should be checked against the original record.

Best used for
  • Subject orientation
  • Search vocabulary
  • Locating named sources
Verify next

The closest primary source, responsible institution and strongest cited specialist reference.

Three-step research path

  1. Establish the record: confirm the title “Serotonin–norepinephrine releasing agent”, its source revision and the description used here.
  2. Expand the search: follow Serotonin–norepinephrine releasing agent primary sources, Serotonin–norepinephrine releasing agent archive and Serotonin research across catalogues and specialist indexes.
  3. Test the account: compare the strongest cited source with the responsible institution’s current record and note any disagreement.

Questions for further research

  1. Which source most directly establishes the central claim about “Serotonin–norepinephrine releasing agent”?
  2. Which institution is responsible for the underlying evidence?
  3. Which cited source is closest to the event, object or claim?
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Source & attribution

This entry incorporates text from “Serotonin–norepinephrine releasing agent” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.