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Syntaphilin

protein-coding gene in the species Homo sapiens

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Record originEnglish Wikipedia
Text licenseCC BY-SA 4.0
Source revisionJun 21, 2026
Entity authorityQ18034644 ↗
Source-derived summary

Syntaphilin is a protein that in humans is encoded by the SNPH gene.

Function

Syntaxin-1, synaptobrevin/VAMP, and SNAP25 interact to form the SNARE complex, which is required for synaptic vesicle docking and fusion. The protein encoded by this gene is membrane-associated and inhibits SNARE complex formation by binding free syntaxin-1. Expression of this gene appears to be brain-specific. Alternative splicing results in multiple transcript variants encoding different isoforms.

References

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

Editorial summary

The public source identifies “Syntaphilin” as protein-coding gene in the species Homo sapiens. This brief keeps that definition visible, then builds a research path around Syntaphilin, protein-coding and gene.

Editorial reviewA sound reference starting point where classification, measurement and the date of the underlying evidence remain visible. The current 89-word lead offers orientation but no explicit four-digit date, so chronology should not be assumed. The selected authority fields contribute no independent date. Its value is orientation rather than verdict, with Syntaphilin, protein-coding and gene providing the first useful test.
Editorial analysis

Why this record matters

A short description can identify a subject without explaining its stakes. For “Syntaphilin”, the useful work is to connect “protein-coding gene in the species Homo sapiens” to the records capable of establishing context and consequence.

Evidence profile

Stable identifiers, scientific names and standards terminology offer the best bridge between this overview and specialist evidence. The source revision retrieved here is dated Jun 21, 2026. The linked authority identifier is Q18034644. None of the 0 selected statements returned an explicit reference.

Critical limits

Scientific names, classifications and consensus can change while older terminology persists in catalogues and historical literature. The lead is largely declarative, so disagreement and counter-evidence require a deliberate search beyond the opening account. Authority statements aid reconciliation but still require their own references, qualifiers and ranks to be checked.

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Source & attribution

This entry incorporates text from “Syntaphilin” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.