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SRSF2

protein-coding gene in the species Homo sapiens

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Record originEnglish Wikipedia
Text licenseCC BY-SA 4.0
Source revisionJul 19, 2025
Entity authorityQ18031455 ↗
Source-derived summary

Serine/arginine-rich splicing factor 2 is a protein that in humans is encoded by the SRSF2 gene. MDS-associated splicing factor SRSF2 affects the expression of Class III and Class IV isoforms and perturbs granulopoiesis and SRSF2 P95H promotes Class IV splicing by binding to key ESE sequences in CSF3R exon 17, and that SRSF2, when mutated, contributes to dysgranulopoiesis.

Interactions

SFRS2 has been shown to interact with CDC5L and ASF/SF2.

Editorial summary

This brief starts where responsible research should: with the source description of “SRSF2” as protein-coding gene in the species Homo sapiens. Everything that follows is an evidence route, not borrowed authority.

Editorial reviewA sound reference starting point where classification, measurement and the date of the underlying evidence remain visible. The current 69-word lead offers orientation but no explicit four-digit date, so chronology should not be assumed. The selected authority fields contribute no independent date. The account is most persuasive where SRSF2, protein-coding and gene can be independently traced.
Editorial analysis

Why this record matters

The subject matters to the science & nature register because the source frames it as protein-coding gene in the species Homo sapiens. Its deeper value depends on whether names, dates, institutions and citations support that framing.

Evidence profile

Datasets, specimens, observations and peer-reviewed methods provide the appropriate test for the technical claims summarized here. The source revision retrieved here is dated Jul 19, 2025. The linked authority identifier is Q18031455. None of the 0 selected statements returned an explicit reference.

Critical limits

A general summary may omit uncertainty, sample limits or methodological disagreement that is explicit in the technical record. The lead is largely declarative, so disagreement and counter-evidence require a deliberate search beyond the opening account. Authority statements aid reconciliation but still require their own references, qualifiers and ranks to be checked.

How to read it

Check terminology, classification and the date of the cited evidence. Scientific names and technical consensus can change while older records retain historical value.

Best used for
  • Current terminology
  • Classification context
  • Finding cited technical literature
Verify next

Primary datasets, specimen catalogues, standards bodies and the most recent peer-reviewed literature.

Three-step research path

  1. Establish the record: confirm the title “SRSF2”, its source revision and the description used here.
  2. Expand the search: follow SRSF2 primary sources, SRSF2 archive and SRSF2 research across catalogues and specialist indexes.
  3. Test the account: compare the strongest cited source with the responsible institution’s current record and note any disagreement.

Questions for further research

  1. Which source most directly establishes the central claim about “SRSF2”?
  2. Which observation, specimen, dataset or publication supports the account?
  3. Is the terminology current, historical or disputed?
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Source & attribution

This entry incorporates text from “SRSF2” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.