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ATP2A2

mammalian protein found in Homo sapiens

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General referenceInterpretive dossier study · Crown Archives visual atlas
Record originEnglish Wikipedia
Text licenseCC BY-SA 4.0
Source revisionSep 3, 2026
Entity authorityQ21115319 ↗
Source-derived summary

ATP2A2 also known as sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) is an ATPase associated with Darier's disease and acrokeratosis verruciformis.

This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in calcium sequestration associated with muscular excitation and contraction. Alternative splicing results in multiple transcript variants encoding different isoforms.

Editorial summary

Begin with the source’s own compact description: “ATP2A2” is mammalian protein found in Homo sapiens. The dossier treats that line as a proposition to test through ATP2A2, mammalian and protein, not as a finished interpretation.

Editorial reviewA dependable orientation record for establishing vocabulary, names and a first evidence trail. The current 85-word lead offers orientation but no explicit four-digit date, so chronology should not be assumed. The selected authority fields contribute no independent date. For this dossier, ATP2A2, mammalian and protein is the immediate research focus.
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Named sources, stable identifiers and responsible institutions provide the strongest route from overview to verifiable evidence. The source revision retrieved here is dated Sep 3, 2026. The linked authority identifier is Q21115319.

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Source & attribution

This entry incorporates text from “ATP2A2” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.