23S rRNA (adenine2503-C2,C8)-dimethyltransferase
obsolete enzyme family
23S rRNA (adenine2503-C2,C8)-dimethyltransferase (EC 2.1.1.194, Cfr, Cfr methyltransferase, Cfr rRNA methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (adenine2503-C2,C8)-dimethyltransferase. This enzyme catalyses the following chemical reaction
2 S-adenosyl-L-methionine + adenine2503 in 23S rRNA
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{\displaystyle \rightleftharpoons }
2 S-adenosyl-L-homocysteine + 2,8-dimethyladenine2503 in 23S rRNA
This enzyme contains an [4Fe-S] cluster.
Begin with the source’s own compact description: “23S rRNA (adenine2503-C2,C8)-dimethyltransferase” is obsolete enzyme family. The dossier treats that line as a proposition to test through rRNA, adenine2503-C2 and -dimethyltransferase, not as a finished interpretation.
Why this record matters
The phrase “obsolete enzyme family” supplies a clear boundary for inquiry. It also exposes the unanswered questions: who defined that boundary, when it became stable and which sources sit outside it.
Vocabulary and entity names are the principal evidence signals here, because they determine the precision of every later search. The source revision retrieved here is dated Aug 2, 2025. The linked authority identifier is Q4631535. None of the 0 selected statements returned an explicit reference.
Overview language is designed for orientation and should not be treated as a substitute for the evidence cited beneath it. The lead is largely declarative, so disagreement and counter-evidence require a deliberate search beyond the opening account. Authority statements aid reconciliation but still require their own references, qualifiers and ranks to be checked.
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Questions for further research
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This entry incorporates text from “23S rRNA (adenine2503-C2,C8)-dimethyltransferase” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.