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TRNA (cytosine34-C5)-methyltransferase

class of enzymes

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General referenceInterpretive dossier study · Crown Archives visual atlas
Record originEnglish Wikipedia
Text licenseCC BY-SA 4.0
Source revisionAug 26, 2023
Entity authorityQ7671434 ↗
Source-derived summary

TRNA (cytosine34-C5)-methyltransferase (EC 2.1.1.203, hTrm4 Mtase, hTrm4 methyltransferase, hTrm4 (gene), tRNA:m5C-methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:tRNA (cytosine34-C5)-methyltransferase. This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + cytosine34 in tRNA precursor

⇌

{\displaystyle \rightleftharpoons }

S-adenosyl-L-homocysteine + 5-methylcytosine34 in tRNA precursor

The human enzyme is specific for C5-methylation of cytosine34 in tRNA precursors.

Editorial summary

The public source identifies “TRNA (cytosine34-C5)-methyltransferase” as class of enzymes. This brief keeps that definition visible, then builds a research path around TRNA, cytosine34-C5 and -methyltransferase.

Editorial reviewA practical starting point whose main value is the path it opens into stronger specialist and primary sources. The current 54-word lead offers orientation but no explicit four-digit date, so chronology should not be assumed. The selected authority fields contribute no independent date. Its value is orientation rather than verdict, with TRNA, cytosine34-C5 and -methyltransferase providing the first useful test.
Editorial analysis

Why this record matters

A short description can identify a subject without explaining its stakes. For “TRNA (cytosine34-C5)-methyltransferase”, the useful work is to connect “class of enzymes” to the records capable of establishing context and consequence.

Evidence profile

Named sources, stable identifiers and responsible institutions provide the strongest route from overview to verifiable evidence. The source revision retrieved here is dated Aug 26, 2023. The linked authority identifier is Q7671434. None of the 0 selected statements returned an explicit reference.

Critical limits

A concise general-reference account can conceal disagreements about scope, terminology or the weight assigned to individual sources. The lead is largely declarative, so disagreement and counter-evidence require a deliberate search beyond the opening account. Authority statements aid reconciliation but still require their own references, qualifiers and ranks to be checked.

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Use the entry as an orientation point, then follow its citations and revision history. Names, dates and institutional relationships should be checked against the original record.

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  1. Establish the record: confirm the title “TRNA (cytosine34-C5)-methyltransferase”, its source revision and the description used here.
  2. Expand the search: follow TRNA (cytosine34-C5)-methyltransferase primary sources, TRNA (cytosine34-C5)-methyltransferase archive and TRNA research across catalogues and specialist indexes.
  3. Test the account: compare the strongest cited source with the responsible institution’s current record and note any disagreement.

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Source & attribution

This entry incorporates text from “TRNA (cytosine34-C5)-methyltransferase” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.