40S ribosomal protein S8
protein-coding gene in the species Homo sapiens
40S ribosomal protein S8 is a protein that in humans is encoded by the RPS8 gene.
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S8E family of ribosomal proteins. It is located in the cytoplasm. Increased expression of this gene in colorectal tumors and colon polyps compared to matched normal colonic mucosa has been observed. This gene is co-transcribed with the small nucleolar RNA genes U38A, U38B, U39, and U40, which are located in its fourth, fifth, first, and second introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
“40S ribosomal protein S8” enters the record as protein-coding gene in the species Homo sapiens. Crown Archives preserves that source wording while asking what ribosomal, protein and protein-coding can confirm, complicate or overturn.
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The date and method of observation matter as much as the stated conclusion, especially where classification or consensus has changed. The source revision retrieved here is dated Aug 29, 2026. The linked authority identifier is Q18031294. None of the 0 selected statements returned an explicit reference.
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