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Psychiatric Genomics Consortium

consortium of psychiatric genomic researchers

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Record originEnglish Wikipedia
Text licenseCC BY-SA 4.0
Source revisionApr 14, 2022
Entity authorityQ65043803
Source-derived summary

The Psychiatric Genomics Consortium (PGC) is an international consortium of scientists dedicated to conducting meta- and mega-analyses of genomic-wide genetic data, with a focus on psychiatric disorders. It is the largest psychiatric consortium ever created, including over 800 researchers from 38 countries as of 2019. Its goal is to generate information about the genetics of psychiatric conditions that will be "actionable", that is, "genetic findings whose biological implications can be used to improve diagnosis, develop rational therapeutics, and craft mechanistic approaches to primary prevention". The consortium makes the main findings from its research freely available for use by other researchers.

History

The PGC was founded in early 2007, originally as the Psychiatric Genome Wide Association Consortium. One of its founders was Patrick F. Sullivan (UNC School of Medicine), who now serves as its lead principal investigator. It was initially a branch of the Genetic Association Information Network, a public-private partnership aimed at researching the genetics of human disorders in general.

For its first four years of existence, the PGC focused on autism spectrum disorder, attention-deficit hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia. It also initially focused only on finding common single nucleotide polymorphisms that were associated with psychiatric disorders. Since then, it has expanded its scope to include other disorders, as well as less common forms of genetic variation such as copy number variation.

Editorial summary

Begin with the source’s own compact description: “Psychiatric Genomics Consortium” is consortium of psychiatric genomic researchers. The dossier treats that line as a proposition to test through Psychiatric, Genomics and Consortium, not as a finished interpretation.

Editorial reviewA dependable orientation record for establishing vocabulary, names and a first evidence trail. The current lead gives the account dated anchors—2019, 2007—that can be checked directly. The selected authority fields contribute no independent date. For this dossier, Psychiatric, Genomics and Consortium is the immediate research focus.
Editorial analysis

Why this record matters

The phrase “consortium of psychiatric genomic researchers” supplies a clear boundary for inquiry. It also exposes the unanswered questions: who defined that boundary, when it became stable and which sources sit outside it.

Evidence profile

The citation trail is more important than the brevity of the summary: it shows where individual claims can be examined in context. The source revision retrieved here is dated Apr 14, 2022. The linked authority identifier is Q65043803. None of the 0 selected statements returned an explicit reference. The first chronological checks are 2019 and 2007.

Critical limits

Overview language is designed for orientation and should not be treated as a substitute for the evidence cited beneath it. The lead is largely declarative, so disagreement and counter-evidence require a deliberate search beyond the opening account. Authority statements aid reconciliation but still require their own references, qualifiers and ranks to be checked.

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Source & attribution

This entry incorporates text from Psychiatric Genomics Consortium” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.