Edogestrone
chemical compound
Edogestrone (INNTooltip International Nonproprietary Name, BANTooltip British Approved Name; development code PH-218; also known as edogesterone or 17α-acetoxy-3,3-ethylenedioxy-6-methylpregn-5-en-20-one) is a steroidal progestin and antiandrogen of the 17α-hydroxyprogesterone group which was synthesized in 1964 but was never marketed. Similarly to the structurally related steroid cyproterone acetate, edogestrone binds directly to the androgen receptor and antagonizes it, displacing androgens like testosterone from the receptor, though not as potently as cyproterone acetate. The drug has also been found to suppress androgen production, likely via progesterone receptor activation-mediated antigonadotropic activity.
“Edogestrone” enters the record as chemical compound. Crown Archives preserves that source wording while asking what Edogestrone, chemical and compound can confirm, complicate or overturn.
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Stable identifiers, scientific names and standards terminology offer the best bridge between this overview and specialist evidence. The source revision retrieved here is dated Jun 22, 2026. The linked authority identifier is Q24884525. None of the 0 selected statements returned an explicit reference. The first chronological checks are 1964.
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This entry incorporates text from “Edogestrone” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.