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P120 catenin

protein-coding gene in the species Homo sapiens

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Record originEnglish Wikipedia
Text licenseCC BY-SA 4.0
Source revisionSep 13, 2026
Entity authorityQ17911598 ↗
Source-derived summary

p120 catenin, or simply p120, also called catenin delta-1, is a protein that in humans is encoded by the CTNND1 gene.

Function

This gene encodes a member of the Armadillo protein family, which function in adhesion between cells and signal transduction. Multiple translation initiation codons and alternative splicing result in many different isoforms being translated. Not all of the full-length natures of the described transcript variants have been determined.

Clinical significance

Either loss or cytoplasmic localization of p120 is a common feature in the progression of several types of carcinoma.

Interactions

CTNND1 has been shown to interact with:

See also

δ-Catenin

Catenin

CTNND2

References

Further reading

External links

Human CTNND1 genome location and CTNND1 gene details page in the UCSC Genome Browser.

Editorial summary

The public source identifies “P120 catenin” as protein-coding gene in the species Homo sapiens. This brief keeps that definition visible, then builds a research path around P120, catenin and protein-coding.

Editorial reviewUseful for establishing the present vocabulary of the subject while preserving a route back to the evidence on which that vocabulary rests. The current 122-word lead offers orientation but no explicit four-digit date, so chronology should not be assumed. The selected authority fields contribute no independent date. Its value is orientation rather than verdict, with P120, catenin and protein-coding providing the first useful test.
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Evidence profile

The date and method of observation matter as much as the stated conclusion, especially where classification or consensus has changed. The source revision retrieved here is dated Sep 13, 2026. The linked authority identifier is Q17911598. None of the 0 selected statements returned an explicit reference.

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Source & attribution

This entry incorporates text from “P120 catenin” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.