Dienestrol
chemical compound
Dienestrol (INNTooltip International Nonproprietary Name, USANTooltip United States Adopted Name) (brand names Dienoestrol, Denestrolin, Dienol and many others), also known as dienoestrol (BANTooltip British Approved Name), is a synthetic nonsteroidal estrogen medication of the stilbestrol group which is or was used to treat menopausal symptoms in the United States and Europe. It has been studied for use by rectal administration in the treatment of prostate cancer in men as well. The medication was introduced in the U.S. in 1947 by Schering as Synestrol and in France in 1948 as Cycladiene. Dienestrol is a close analogue of diethylstilbestrol. It has approximately 223% and 404% of the affinity of estradiol at the ERα and ERβ, respectively.
Dienestrol diacetate (brand names Faragynol, Gynocyrol, others) also exists and has been used medically.
“Dienestrol” enters the record as chemical compound. Crown Archives preserves that source wording while asking what Dienestrol, chemical and compound can confirm, complicate or overturn.
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The date and method of observation matter as much as the stated conclusion, especially where classification or consensus has changed. The source revision retrieved here is dated Aug 4, 2026. The linked authority identifier is Q61734143. None of the 0 selected statements returned an explicit reference. The first chronological checks are 1947 and 1948.
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