Phenylacetaldoxime dehydratase
class of enzymes
In enzymology, a phenylacetaldoxime dehydratase (EC 4.99.1.7) is an enzyme that catalyzes the chemical reaction
(Z)-phenylacetaldehyde oxime
⇌
{\displaystyle \rightleftharpoons }
phenylacetonitrile + H2O
Hence, this enzyme has one substrate, (Z)-phenylacetaldehyde oxime, and two products, phenylacetonitrile and H2O.
This enzyme belongs to the family of lyases, specifically the "catch-all" class of lyases that do not fit into any other sub-class. The systematic name of this enzyme class is (Z)-phenylacetaldehyde-oxime hydro-lyase (phenylacetonitrile-forming). Other names in common use include PAOx dehydratase, arylacetaldoxime dehydratase, OxdB, and (Z)-phenylacetaldehyde-oxime hydro-lyase. This enzyme participates in styrene degradation.
References
Kato Y, Nakamura K, Sakiyama H, Mayhew SG, Asano Y (2000). "Novel heme-containing lyase, phenylacetaldoxime dehydratase from Bacillus sp. strain OxB-1: purification, characterization, and molecular cloning of the gene". Biochemistry. 39 (4): 800–9. doi:10.1021/bi991598u.
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