Nucleoprotein
proteins conjugated with nucleic acids
Nucleoproteins are complexes formed by proteins conjugated with nucleic acids (either DNA or RNA). However It could sometimes mean just a protein relevant to nucleic acid. Typical nucleoproteins include ribosomes, nucleosomes and viral nucleocapsid (caspid + viral genome).
Structures
Nucleoproteins tend to be positively charged. The fact facilitates their interaction with the negatively charged nucleic acid chains. The tertiary structures and biological functions of many nucleoproteins are understood. Important techniques for finding the structures of nucleoproteins include X-ray diffraction, nuclear magnetic resonance and cryo-electron microscopy.
Viruses
Virus genomes (either DNA or RNA) are extremely tightly packed into the viral capsid. Many viruses are therefore little more than an organised collection of nucleoproteins with their binding sites pointing inwards. Structurally characterised viral nucleoproteins include influenza, rabies, Ebola, Bunyamwera, Schmallenberg, Hazara, Crimean-Congo hemorrhagic fever, and Lassa.
The public source identifies “Nucleoprotein” as proteins conjugated with nucleic acids. This brief keeps that definition visible, then builds a research path around Nucleoprotein, proteins and conjugated.
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Named sources, stable identifiers and responsible institutions provide the strongest route from overview to verifiable evidence. The source revision retrieved here is dated Sep 10, 2026. The linked authority identifier is Q419245. The Library of Congress control number is sh85093155. 1 of 1 selected statements include explicit references; 1 carry qualifiers and 0 use preferred rank.
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This entry incorporates text from “Nucleoprotein” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.