NBPF8
protein-coding gene in the species Homo sapiens
Neuroblastoma breakpoint family member 8 (NBPF8) is a protein which, in Homo sapiens (humans), is encoded by the NBPF8 gene.
Gene
NBPF8 is a member of the neuroblastoma breakpoint family (NBPF), and it is located on the plus strand of human chromosome 1 at the location of 1p11.2. This gene contains 19 exons and spans 7,256 base pairs; however, its coding sequence spans 2,828 base pairs.
mRNA
The mRNA of the NBPF8 Transcript Variant 1 includes 7,526 nucleotides, and this is the isoform that will be described in detail in this page. Additionally, there are two other isoforms of the NBPF8 that encode proteins which are NBPF8 Isoform X1 and NBPF8 Isoform X2 which span 6,826 nucleotides and 3,894 nucleotides, respectively. The non-protein coding isoforms of NBPF8 are NBPF8 Transcript Variant 2 and NBPF8 Transcript Variant 3 which span 7,360 nucleotides and 7,100 nucleotides, respectively.
Protein
The NBPF8 protein encoded by NBPF8 Transcript Variant 1 contains 942 amino acids, has a molecular weight of 10.9kD, and an isoelectric point equal to 4.7. The two protein-coding isoforms mentioned previously, NBPF8 Isoform X1 and NBPF8 Isoform X2 encode 1,353 and 872 amino acids, respectively.
Compositional analysis
The NBPF8 protein in Homo sapiens has more glutamic acid and glutamine (amino acids) than the average protein while having less threonine than the typical protein.
The NBPF8 protein in Aotus nancymaae, the furthest ortholog of the NBPF8 gene and protein from humans, also has more glutamic acid and glutamine (amino acids) than the average protein while having less threonine than the typical protein, therefore aligning with the NBPF8 protein in humans.
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The subject matters to the science & nature register because the source frames it as protein-coding gene in the species Homo sapiens. Its deeper value depends on whether names, dates, institutions and citations support that framing.
Datasets, specimens, observations and peer-reviewed methods provide the appropriate test for the technical claims summarized here. The source revision retrieved here is dated Feb 28, 2026. The linked authority identifier is Q18061559. None of the 0 selected statements returned an explicit reference.
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This entry incorporates text from “NBPF8” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.