Benjamin Neale
statistical geneticist
Benjamin Michael Neale is a statistical geneticist with a specialty in psychiatric genetics. He is an institute member at the Broad Institute as well as an associate professor at both Harvard Medical School and the Analytic and Translational Genetics Unit at Massachusetts General Hospital. Neale specializes in genome-wide association studies (GWAS). He was responsible for the data analysis of the first GWAS on attention-deficit/hyperactivity-disorder, and he developed new analysis software such as PLINK, which allows for whole-genome data to be analyzed for specific gene markers. Related to his work on GWAS, Neale is the lead of the ADHD psychiatric genetics and also a member of the Psychiatric GWAS Consortium analysis committee.
Education
Neale's academic background includes a Genetics Bachelor's of Science degree from the University of Chicago and a Ph.D. in human genetics from King's College. His postdoctoral project was done in the laboratory of Mark Daly at Massachusetts General Hospital. Neale was recently awarded the 2020 Early-Career Award by the American Society of Human Genetics for his emphasis on using statistical methodology in his research analyses.
Research
Neale has published work on autism and genetic contributions to disease. In 2010, Neale wrote about the function of the hepatic lipase gene, LIPC. The experiment found an association between advanced age-related macular degeneration (AMD), which is the main culprit of late onset blindness, and genetic variants in LIPC of the high-density lipoprotein cholesterol (HDL) pathway.
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