Procarbazine
chemical compound
Procarbazine is a chemotherapy medication used for the treatment of Hodgkin lymphoma and brain cancers. For Hodgkin lymphoma it is often used together with chlormethine, vincristine, and prednisone while for brain cancers such as glioblastoma multiforme it is used with lomustine and vincristine. It is typically taken by mouth.
Common side effect include low blood cell counts and vomiting. Other side effects include tiredness and depression. It is not recommended in people with severe liver or kidney problems. Use in pregnancy is known to harm the baby. Procarbazine is in the alkylating agents family of medication. How it works is not clearly known.
Procarbazine was approved for medical use in the United States in 1969.
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Stable identifiers, scientific names and standards terminology offer the best bridge between this overview and specialist evidence. The source revision retrieved here is dated Feb 12, 2026. The linked authority identifier is Q418656. None of the 0 selected statements returned an explicit reference. The first chronological checks are 1969.
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This entry incorporates text from “Procarbazine” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.