Isosorbide mononitrate
chemical compound
Isosorbide mononitrate, sold under many brand names, is a medication used for heart-related chest pain (angina), heart failure and esophageal spasms. It can be used both to treat and to prevent heart-related chest pain; however, it is generally less preferred than beta blockers or calcium channel blockers. It is taken by mouth.
Common side effects include headache, low blood pressure with standing, blurry vision, and skin flushing. Serious side effects may include low blood pressure especially if also exposed to PDE5 inhibitors such as sildenafil. Use is not recommended in pregnancy. It is believed to work by relaxing smooth muscle within blood vessels.
It was patented in 1971 and approved for medical use in 1981. It is available as a generic medication. In 2023, isosorbide was the 125th most commonly prescribed medication in the United States, with more than 5 million prescriptions.
“Isosorbide mononitrate” enters the record as chemical compound. Crown Archives preserves that source wording while asking what Isosorbide, mononitrate and chemical can confirm, complicate or overturn.
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Datasets, specimens, observations and peer-reviewed methods provide the appropriate test for the technical claims summarized here. The source revision retrieved here is dated May 27, 2026. The linked authority identifier is Q423401. None of the 0 selected statements returned an explicit reference. The first chronological checks are 1971, 1981 and 2023.
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This entry incorporates text from “Isosorbide mononitrate” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.