Minimum information required in the annotation of models
Open-knowledge reference entry

MIRIAM (Minimum Information Required In The Annotation of Models) is a community-level effort to standardize the annotation and curation processes of quantitative models of biological systems. It consists of a set of guidelines suitable for use with any structured format, allowing different groups to collaborate and share resulting models. Adherence to these guidelines also facilitates the sharing of software and service infrastructures built upon modeling activities.
The idea of "a set of good practices" including "some obligatory metadata" was first proposed by Nicolas Le Novère in October 2004 as part of a discussion to develop a common database of models in systems biology (which led to the creation of BioModels Database). These initial ideas were further refined at a meeting in Heidelberg, during ICSB 2004, with representatives from many other interested groups.
MIRIAM is a registered project of the MIBBI (minimum information for biological and biomedical investigations).
MIRIAM Guidelines
The MIRIAM Guidelines are composed of three parts, reference correspondence, attribution annotation, and external resource annotation, each of which deals with a different aspect of information that should be included within a model.
Reference correspondence
'Reference correspondence' deals with the basic reference information needed to make use of the model, detailing on a gross level the format of the model file, and its instantiability for simulation purposes.
The model file must be encoded in a public, standardized, machine-readable format (SBML, CellML, GENESIS, ...).
The model file must be valid with respect to its encoding schema.
Begin with the source’s own compact description: “Minimum information required in the annotation of models” is open-knowledge reference entry. The dossier treats that line as a proposition to test through Minimum, information and required, not as a finished interpretation.
Why this record matters
The phrase “open-knowledge reference entry” supplies a clear boundary for inquiry. It also exposes the unanswered questions: who defined that boundary, when it became stable and which sources sit outside it.
The citation trail is more important than the brevity of the summary: it shows where individual claims can be examined in context. The source revision retrieved here is dated Nov 22, 2025. The linked authority identifier is Q3315070. None of the 0 selected statements returned an explicit reference. The first chronological checks are 2004.
Overview language is designed for orientation and should not be treated as a substitute for the evidence cited beneath it. The lead is largely declarative, so disagreement and counter-evidence require a deliberate search beyond the opening account. Authority statements aid reconciliation but still require their own references, qualifiers and ranks to be checked.
How to read it
Use the entry as an orientation point, then follow its citations and revision history. Names, dates and institutional relationships should be checked against the original record.
- Subject orientation
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The closest primary source, responsible institution and strongest cited specialist reference.
Three-step research path
- Establish the record: confirm the title “Minimum information required in the annotation of models”, its source revision and the description used here.
- Expand the search: follow Minimum information required in the annotation of models primary sources, Minimum information required in the annotation of models archive and Minimum research across catalogues and specialist indexes.
- Test the account: compare the strongest cited source with the responsible institution’s current record and note any disagreement.
Questions for further research
- Which source most directly establishes the central claim about “Minimum information required in the annotation of models”?
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This entry incorporates text from “Minimum information required in the annotation of models” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.