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MCC (gene)

protein-coding gene in the species Homo sapiens

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Science and natureInterpretive dossier study · Crown Archives visual atlas
Record originEnglish Wikipedia
Text licenseCC BY-SA 4.0
Source revisionJul 19, 2025
Entity authorityQ18028926 ↗
Source-derived summary

Colorectal mutant cancer protein is a protein that in humans is encoded by the MCC gene.

This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene.

Editorial summary

“MCC (gene)” enters the record as protein-coding gene in the species Homo sapiens. Crown Archives preserves that source wording while asking what gene, protein-coding and species can confirm, complicate or overturn.

Editorial reviewUseful for establishing the present vocabulary of the subject while preserving a route back to the evidence on which that vocabulary rests. The current 74-word lead offers orientation but no explicit four-digit date, so chronology should not be assumed. The selected authority fields contribute no independent date. Its strongest next move is a source search built around gene, protein-coding and species.
Editorial analysis

Why this record matters

“MCC (gene)” is worth following because a concise public description often conceals a longer documentary argument. Here, gene, protein-coding and species provides the most credible route into that argument.

Evidence profile

Datasets, specimens, observations and peer-reviewed methods provide the appropriate test for the technical claims summarized here. The source revision retrieved here is dated Jul 19, 2025. The linked authority identifier is Q18028926. None of the 0 selected statements returned an explicit reference.

Critical limits

A general summary may omit uncertainty, sample limits or methodological disagreement that is explicit in the technical record. The lead is largely declarative, so disagreement and counter-evidence require a deliberate search beyond the opening account. Authority statements aid reconciliation but still require their own references, qualifiers and ranks to be checked.

How to read it

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Primary datasets, specimen catalogues, standards bodies and the most recent peer-reviewed literature.

Three-step research path

  1. Establish the record: confirm the title “MCC (gene)”, its source revision and the description used here.
  2. Expand the search: follow MCC (gene) primary sources, MCC (gene) archive and gene research across catalogues and specialist indexes.
  3. Test the account: compare the strongest cited source with the responsible institution’s current record and note any disagreement.

Questions for further research

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  2. Has classification or technical consensus changed since the cited source?
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Source & attribution

This entry incorporates text from “MCC (gene)” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.