Maryland Route 381
highway in Maryland

Maryland Route 381 (MD 381) is a state highway in the U.S. state of Maryland. Known as Brandywine Road, the highway runs 15.91 miles (25.60 km) from MD 231 at Patuxent north to U.S. Route 301 (US 301) in Brandywine. MD 381 connects Brandywine with the southeastern corner of Prince George's County and the northeastern corner of Charles County. The highway was constructed from MD 5 through Brandywine in the 1910s. MD 381 was extended southeast to MD 231 in the late 1920s and early 1930s. When MD 5 was relocated between Camp Springs and Brandywine in the mid-1950s, MD 381 was extended north along the old road to Camp Springs. The highway was rolled back to its present terminus at US 301 in the mid-1960s. The route can serve as an alternate route to the more heavily traveled MD 5 for those wanting to go from St. Mary's, Calvert, and eastern Charles counties to Brandywine.
Route description
MD 381 begins at an intersection with MD 231 (Prince Frederick Road) at the hamlet of Patuxent between Hughesville and the Patuxent River.
Begin with the source’s own compact description: “Maryland Route 381” is highway in Maryland. The dossier treats that line as a proposition to test through Maryland, Route and highway, not as a finished interpretation.
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Vocabulary and entity names are the principal evidence signals here, because they determine the precision of every later search. The source revision retrieved here is dated May 4, 2025. The linked authority identifier is Q2480467. 1 of 1 selected statements include explicit references; 0 carry qualifiers and 0 use preferred rank.
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This entry incorporates text from “Maryland Route 381” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.