Martin J. Lohse
German physician and pharmacologist
Martin J. Lohse (born 26 August 1956) is a German physician and pharmacologist.
Career
Lohse performs ongoing research on G protein-coupled receptors. Since 1993, he is a Professor of Pharmacology at the University of Würzburg, Germany, retired in 2022, and he was the Founding Chairman of the Rudolf Virchow Center (2001–2016). From 2016 to 2019, he was Chairman of the Board and Scientific Director of the Max Delbrück Center in Berlin, a national research center of the Helmholtz Association for molecular medicine. In 2017, he also became Speaker of the Board of the Berlin Institute of Health, a joint research center of the Max Delbrück Center and the Charité. Since 2020 he is chairman and managing director of ISAR Bioscience Institute, a translational research institute in Planegg/Munich.
Lohse received his exam in medicine as well as his M.D. from the University of Göttingen, and did research in pharmacology at the University of Heidelberg, Duke University and the GeneCenter in Munich. His research focusses on the role of receptors in heart failure and on the mechanisms of their activation and inactivation.
While working with Robert Lefkowitz at Duke University he discovered beta-arrestins, proteins that regulate the function of certain cell surface receptors.
He discovered that beta-1 adrenergic receptors and their regulatory G protein-coupled receptor kinases are dysregulated in heart failure.
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This entry incorporates text from “Martin J. Lohse” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.