Mark A. Kay
American pediatrician and developmental genetics researcher
Mark A. Kay is an American physician-scientist recognized for his contributions to the field of gene therapy, genome editing, and RNA biology. He has an h-index of 123, and is known for liver-directed gene therapy, demonstrating RNA interference in mammals, and advancing adeno-associated virus (AAV) vector biology.
Education
Kay earned his B.S. in Physical Sciences from Lyman Briggs College at Michigan State University in 1980, and his M.D. and Ph.D. in Developmental Genetics from Case Western Reserve University in 1987. He completed a pediatric residency, medical genetics fellowship, and postdoctoral fellowship at Baylor College of Medicine in 1993.
Career and research
Kay began his work in gene therapy in 1990. He was a founding member of the American Society of Gene and Cell Therapy (ASGCT) in 1996 and served as its Vice President, President-Elect, and President from 2003 to 2006. He played a role in establishing the society’s journal, Molecular Therapy, and advancing gene therapy research during a period of skepticism.
Kay has been a long-time editor of Human Gene Therapy. His research has led to advances in gene transfer mechanisms, vector biology, and gene regulation. He demonstrated the correction of Hemophilia B in a large animal model and filed the initial Investigational New Drug (IND) application for systemic administration of recombinant AAV in humans.
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The entry’s evidential value lies in the named roles, institutions and publications that can be tested against primary documentation. The source revision retrieved here is dated Aug 31, 2026. The linked authority identifier is Q59750959. VIAF identifies the subject as 60698774. The Library of Congress control number is n90609456. None of the 3 selected statements returned an explicit reference. The first chronological checks are 1980, 1987, 1993 and 1990.
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This entry incorporates text from “Mark A. Kay” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.