Monooxygenase DBH-like 1
protein-coding gene in the species Homo sapiens
DBH-like monooxygenase protein 1, also known as monooxygenase X, is an enzyme that in humans is encoded by the MOXD1 gene.
DBH-like 1 maintains many of the structural features of dopamine beta-monooxygenase DBH. Since Peptidylglycine alpha-hydroxylating monooxygenase (PHM; EC 1.14.17.3) is homologous to dopamine beta-monooxygenase (DBM; EC 1.14.17.1) this concerns a structural basis for a new family of copper type II, significantly specific for ascorbate-dependent monooxygenases based on the corresponding mouse homolog. The pathway of catecholamine synthesis is a possible catecholamine-binding metabolic copper enzyme domain, a neuron-like property encoding MOX without a signal sequence enzyme metabolism resolving the monooxygenase X chemical pathway of an unknown substrate, exogenous MOX is not secreted, and it localizes throughout the endoplasmic reticulum, in both endocrine or nonendocrine cells.
Deficiency
DBH deficiency has been treated effectively with L-threo-3,4-dihydroxyphenylserine (DOPS).
“Monooxygenase DBH-like 1” enters the record as protein-coding gene in the species Homo sapiens. Crown Archives preserves that source wording while asking what Monooxygenase, DBH-like and protein-coding can confirm, complicate or overturn.
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The date and method of observation matter as much as the stated conclusion, especially where classification or consensus has changed. The source revision retrieved here is dated Jul 30, 2025. The linked authority identifier is Q18037864. None of the 0 selected statements returned an explicit reference.
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