Lymphoid leukemia
malignant lymphocytic neoplasm of B-cell or T-cell lineage involving primarily the bone marrow and the peripheral blood
Lymphoid leukemias are a group of leukemias affecting circulating lymphocytes, a type of white blood cell. The lymphocytic leukemias are closely related to lymphomas of the lymphocytes, to the point that some of them are unitary disease entities that can be called by either name (for example, adult T-cell leukemia/lymphoma). Such diseases are all lymphoproliferative disorders. Most lymphoid leukemias involve a particular subtype of lymphocytes, the B cells.
Classification
Historically, they have been most commonly divided by the stage of maturation at which the clonal (neoplastic) lymphoid population stopped maturing:
Acute lymphoblastic leukemia
Chronic lymphocytic leukemia
However, the influential WHO Classification (published in 2001) emphasized a greater emphasis on cell lineage. To this end, lymphoid leukemias can also be divided by the type of cells affected:
B-cell leukemia
T-cell leukemia
NK-cell leukemia
The most common type of lymphoid leukemia is B-cell chronic lymphocytic leukemia.
B-cell leukemias
B-cell leukemia describes several different types of lymphoid leukemia which affect B cells.
Other types include (with ICD-O code):
9826/3 – Acute lymphoblastic leukemia, mature B-cell type
9833/3 – B-cell prolymphocytic leukemia
9940/3 – Hairy cell leukemia
T-cell leukemias
T-cell leukemia describes several different types of lymphoid leukemias which affect T cells.
The most common T-cell leukemia is precursor T-cell lymphoblastic leukemia. It causes 15% of acute leukemias in childhood, and also 40% of lymphomas in childhood.
Begin with the source’s own compact description: “Lymphoid leukemia” is malignant lymphocytic neoplasm of B-cell or T-cell lineage involving primarily the bone marrow and the peripheral blood. The dossier treats that line as a proposition to test through Lymphoid, leukemia and malignant, not as a finished interpretation.
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The phrase “malignant lymphocytic neoplasm of B-cell or T-cell lineage involving primarily the bone marrow and the peripheral blood” supplies a clear boundary for inquiry. It also exposes the unanswered questions: who defined that boundary, when it became stable and which sources sit outside it.
Vocabulary and entity names are the principal evidence signals here, because they determine the precision of every later search. The source revision retrieved here is dated Jul 12, 2026. The linked authority identifier is Q6708277. None of the 0 selected statements returned an explicit reference. The first chronological checks are 2001.
The absence of detail may reflect summary conventions rather than a lack of surviving documentation. The source lead contains qualifying language; that uncertainty should survive quotation, summary and reuse. Authority statements aid reconciliation but still require their own references, qualifiers and ranks to be checked.
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This entry incorporates text from “Lymphoid leukemia” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.