Lymphatogenous metastasis
Effect of cancer

Lymphatogenous metastasis is the spread of cancer from the vulva, clitoris and Bartholin glands. As these other more superficial cancers grow deeper into the surrounding tissue, the risk of lymphatogenous metastasis increases. Vulvar cancers spread primarily to the inguinofemoral lymph nodes. From these lymph nodes, cancer can spread to the pelvic lymph nodes.
Risk
If the depth of the cancer on the vulva, clitoris or Bartholin gland is less than 1 mm, lymphatogenous metastasis is relatively unlikely. When the growth is between 1 and 3 mm in depth, the risk of lymphatogenous metastasis approaches 8%. At the depths of more than 3 mm, the involvement of lymph nodes is expected in at least 20% of the time. Risk continues to increase along with the possibility of contralateral metastasis. Other growth characteristics influence risk of the spread such as the mass of the original growth, the initial location.
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This entry incorporates text from “Lymphatogenous metastasis” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.