Löffler's syndrome
Human disease
Löffler's syndrome is a disease in which eosinophils accumulate in the lung in response to a parasitic infection. The parasite can be Ascaris, Strongyloides stercoralis, or Dirofilaria immitis which can enter the body through contact with the soil. The symptoms of Löffler's syndrome include those of a parasitic infection such as abdominal pain and cramping, skin rashes and fatigue. Löffler's syndrome itself will cause difficulty breathing, wheeze, coughing as well as a fever.
Diagnosis
The diagnosis of Loffler's syndrome can be challenging, as the diagnostic criteria can be vague and consistent with a multitude of diseases or conditions. The disease's developmental trajectory is mostly unknown. Upon examination of symptoms, a doctor will likely request a chest x-ray looking for migratory pulmonary infiltrate, and blood testing, to confirm a diagnosis. Symptoms tend to be brief, but can range from mild to severe and include: fever, vomiting, increased respirations or difficulty breathing, cough, wheeze, and rash. Symptoms typically follow an exposure to allergens or certain drugs, and last approximately two weeks.
Eosinophilia is the main feature of diagnostic criteria for Loffler's syndrome.
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