Lycorine
chemical compound

Lycorine is a toxic crystalline alkaloid found in various Amaryllidaceae species, such as the cultivated bush lily (Clivia miniata), surprise lilies (Lycoris), and daffodils (Narcissus). It may be highly poisonous, or even lethal, when ingested in certain quantities. Regardless, it is sometimes used as a component in traditional medicines.
Source
Lycorine is found in different species of Amaryllidaceae which include flowers and bulbs of daffodil, snowdrop (Galanthus) or spider lily (Lycoris). Lycorine is the most frequent alkaloid of Amaryllidaceae.
A 2014 research paper suggested that the earliest diversification of the Amaryllidaceae likely occurred in North Africa and the Iberian Peninsula. Furthermore, the study concluded that the biosynthetic pathway responsible for lycorine production is the oldest among the various toxin synthesis pathways found within the Amaryllidaceae.
Mechanism of action
There is currently very little known about the mechanism of action of lycorine, although there have been some tentative hypotheses advanced concerning the metabolism of the alkaloid, based on experiments carried out upon beagle dogs.
Lycorine impedes protein synthesis in animal and fungal cells.
It is known that lycorine weakly inhibits acetylcholinesterase (AChE) and ascorbic acid biosynthesis.
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This entry incorporates text from “Lycorine” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.