Lepromin skin test
skin test for leprosy
The lepromin skin test is used to determine what type of leprosy a person is infected with. It involves the injection of a standardized extract of the inactivated "leprosy bacillus" (Mycobacterium leprae or "Hansen's bacillus") under the skin. It is not recommended as a primary mode of diagnosis.
Method
Positive reaction means: A) 10 mm (0.39 in) or more induration after 48hrs B) 5 mm (0.20 in) or above nodule after 21 days. An extract sample of inactivated Hansen's bacillus is injected just under the skin, usually on the forearm, so that a small lump pushes the skin upward. The lump indicates that the antigen has been injected at the correct depth. The injection site is labeled and examined at 48 hours and 21 days later to see if there is a reaction.
People with dermatitis or other skin irritations should have the test performed on an unaffected part of the body. When the antigen is injected, there may be a slight stinging or burning sensation. There may also be mild itching at the site of injection afterwards.
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