Alanine—oxo-acid transaminase
enzyme within the transanimase family
Alanine-oxo-acid transaminase (EC 2.6.1.12) is an enzyme characterised in Brucella abortus and some plants that catalyzes a general chemical reaction that converts L-alanine and an α-keto acid into pyruvic acid and an L-amino acid:
L-alanine + a 2-oxo acid
⇌
{\displaystyle \rightleftharpoons }
pyruvic acid + an L-amino acid
For example, reaction with α-ketoglutaric acid gives L-aspartic acid:
This enzyme is a transferase, specifically a transaminase, which transfer nitrogenous groups. The systematic name of this enzyme class is L-alanine:2-oxo-acid aminotransferase. Other names in common use include L-alanine-alpha-keto acid aminotransferase, leucine-alanine transaminase, alanine-keto acid aminotransferase, and alanine-oxo acid aminotransferase. It uses pyridoxal phosphate as a cofactor.
The public source identifies “Alanine—oxo-acid transaminase” as enzyme within the transanimase family. This brief keeps that definition visible, then builds a research path around Alanine, oxo-acid and transaminase.
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This entry incorporates text from “Alanine—oxo-acid transaminase” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.