Multiple myeloma
cancer of plasma cells
Multiple myeloma (MM), also known as plasma cell myeloma and simply myeloma, is a cancer of plasma cells, a type of white blood cell that normally produces antibodies. Often, no symptoms are noticed initially. As it progresses, bone pain, anemia, renal insufficiency, and infections may occur. Complications may include hypercalcemia and amyloidosis.
The cause of multiple myeloma is unknown. Risk factors include obesity, radiation exposure, family history, age and certain chemicals. There is an increased risk of multiple myeloma in certain occupations, due to occupational exposure to aromatic hydrocarbon solvents. Multiple myeloma is the result of a multi-step malignant transformation, and almost universally originates from the pre-malignant stage monoclonal gammopathy of undetermined significance (MGUS). As MGUS evolves into MM, another pre-stage of the disease is reached, known as smoldering myeloma (SMM).
In MM, the abnormal plasma cells produce abnormal antibodies, which can cause kidney problems and overly thick blood.
“Multiple myeloma” enters the record as cancer of plasma cells. Crown Archives preserves that source wording while asking what Multiple, myeloma and cancer can confirm, complicate or overturn.
Why this record matters
“Multiple myeloma” is worth following because a concise public description often conceals a longer documentary argument. Here, Multiple, myeloma and cancer provides the most credible route into that argument.
Vocabulary and entity names are the principal evidence signals here, because they determine the precision of every later search. The source revision retrieved here is dated Sep 15, 2026. The linked authority identifier is Q467635. The Library of Congress control number is sh85088367. 1 of 1 selected statements include explicit references; 1 carry qualifiers and 0 use preferred rank.
A concise general-reference account can conceal disagreements about scope, terminology or the weight assigned to individual sources. The source lead contains qualifying language; that uncertainty should survive quotation, summary and reuse. Authority statements aid reconciliation but still require their own references, qualifiers and ranks to be checked.
How to read it
Use the entry as an orientation point, then follow its citations and revision history. Names, dates and institutional relationships should be checked against the original record.
- Subject orientation
- Search vocabulary
- Locating named sources
The closest primary source, responsible institution and strongest cited specialist reference.
Three-step research path
- Establish the record: confirm the title “Multiple myeloma”, its source revision and the description used here.
- Expand the search: follow Multiple myeloma primary sources, Multiple myeloma archive and Multiple research across catalogues and specialist indexes.
- Test the account: compare the strongest cited source with the responsible institution’s current record and note any disagreement.
Questions for further research
- Which source most directly establishes the central claim about “Multiple myeloma”?
- Which cited source is closest to the event, object or claim?
- Which institution is responsible for the underlying evidence?
Search terms from this dossier
This entry incorporates text from “Multiple myeloma” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.