KLK13
gene of the species Homo sapiens
Kallikrein-13 is a protein that in humans is encoded by the KLK13 gene.
Function
Kallikreins are a subgroup of serine proteases having diverse physiological functions.
As of 2022, the precise physiological functions of Kallikrein 13 remain unknown. It may play a role in the defense of the upper digestive apparatus, in extracellular matrix degradation, in tissue remodelling, and in the male reproductive organs.
This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Expression of this gene is regulated by steroid hormones and may be useful as a marker for breast cancer. An additional transcript variant has been identified, but its full length sequence has not been determined.
Kallikrein-13 serves as a priming protease during infection by the human coronavirus HKU1.
Many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers.
This brief starts where responsible research should: with the source description of “KLK13” as gene of the species Homo sapiens. Everything that follows is an evidence route, not borrowed authority.
Why this record matters
The subject matters to the science & nature register because the source frames it as gene of the species Homo sapiens. Its deeper value depends on whether names, dates, institutions and citations support that framing.
Datasets, specimens, observations and peer-reviewed methods provide the appropriate test for the technical claims summarized here. The source revision retrieved here is dated Sep 7, 2026. The linked authority identifier is Q18038062. None of the 0 selected statements returned an explicit reference. The first chronological checks are 2022.
A general summary may omit uncertainty, sample limits or methodological disagreement that is explicit in the technical record. The source lead contains qualifying language; that uncertainty should survive quotation, summary and reuse. Authority statements aid reconciliation but still require their own references, qualifiers and ranks to be checked.
How to read it
Check terminology, classification and the date of the cited evidence. Scientific names and technical consensus can change while older records retain historical value.
- Current terminology
- Classification context
- Finding cited technical literature
Primary datasets, specimen catalogues, standards bodies and the most recent peer-reviewed literature.
Three-step research path
- Establish the record: confirm the title “KLK13”, its source revision and the description used here.
- Expand the search: follow KLK13 primary sources, KLK13 archive and KLK13 research across catalogues and specialist indexes.
- Test the account: compare the strongest cited source with the responsible institution’s current record and note any disagreement.
Questions for further research
- Which source most directly establishes the central claim about “KLK13”?
- Has classification or technical consensus changed since the cited source?
- Is the terminology current, historical or disputed?
Search terms from this dossier
This entry incorporates text from “KLK13” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.